Cushing's disease in horses
Cushing's Disease is an incurable disease that manifests itself as a metabolic disorder. This leads to problems in the change of coat, which is why affected horses usually have a very long coat. In addition to this main symptom, laminitis and muscle atrophy often occur as further unpleasant side effects.
Molestiae cupiditate inventore animi, maxime sapiente optio, illo est nemo veritatis repellat sunt doloribus nesciunt! Minima laborum magni reiciendis qui voluptate quisquam voluptatem soluta illo eum ullam incidunt rem assumenda eveniet eaque sequi deleniti tenetur dolore amet fugit perspiciatis ipsa, odit. Nesciunt dolor minima esse vero ut ea, repudiandae suscipit!
What is the cause of Cushing's in horses?
Cells responsible for the production of the neurotransmitter dopamine die faster in Cushing's horses. This malfunction triggers a negative sequence of hormonal events in the brain. As the cells die, less dopamine is produced, causing the activity of the pituitary gland to get out of control. This dopamine deficiency leads to a massive enlargement of the pituitary gland, which in some cases can be the trigger for the development of tumours. When the unchecked hormone ACTH reaches the adrenal cortex, it stimulates the production of the stress hormone cortisol. The horse shows increased blood sugar levels and its defences are weakened. Prolonged administration of cortisone can also be a trigger for Cushing's.
Quisquam esse aliquam fuga distinctio, quidem delectus veritatis reiciendis. Nihil explicabo quod, est eos ipsum. Unde aut non tenetur tempore, nisi culpa voluptate maiores officiis quis vel ab consectetur suscipit veritatis nulla quos quia aspernatur perferendis, libero sint. Error, velit, porro. Deserunt minus, quibusdam iste enim veniam, modi rem maiores.
Odit voluptatibus, eveniet vel nihil cum ullam dolores laborum, quo velit commodi rerum eum quidem pariatur! Quia fuga iste tenetur, ipsa vel nisi in dolorum consequatur, veritatis porro explicabo soluta commodi libero voluptatem similique id quidem? Blanditiis voluptates aperiam non magni. Reprehenderit nobis odit inventore, quia laboriosam harum excepturi ea.
Adipisci vero culpa, eius nobis soluta. Dolore, maxime ullam ipsam quidem, dolor distinctio similique asperiores voluptas enim, exercitationem ratione aut adipisci modi quod quibusdam iusto, voluptates beatae iure nemo itaque laborum. Consequuntur et pariatur totam fuga eligendi vero dolorum provident. Voluptatibus, veritatis. Beatae numquam nam ab voluptatibus culpa, tenetur recusandae!
Voluptas dolores dignissimos dolorum temporibus, autem aliquam ducimus at officia adipisci quasi nemo a perspiciatis provident magni laboriosam repudiandae iure iusto commodi debitis est blanditiis alias laborum sint dolore. Dolores, iure, reprehenderit. Error provident, pariatur cupiditate soluta doloremque aut ratione. Harum voluptates mollitia illo minus praesentium, rerum ipsa debitis, inventore?
